With some worth knowing information about grooming Guinea Pigs it will be quite easy to keep them fit and happy.
At the beginning it might seem quite difficult for you and also for your cavies and you may feel overstrained but with some practice it won’t be a problem anymore.
Carefully grooming Guinea Pigs is the best you can do to prevent diseases and not at least to minimize tang in the cage / room.
Weekly you should to the healthy check.